Manipulating the NKG2D Receptor-Ligand Axis Using CRISPR: Novel Technologies for Improved Host Immunity
The activating immune receptor natural killer group member D Salad Spinner (NKG2D) and its cognate ligands represent a fundamental surveillance system of cellular distress, damage or transformation.Signaling through the NKG2D receptor-ligand axis is critical for early detection of viral infection or oncogenic transformation and the presence of func